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In: drug discovery

19 Jun, 2019The Effects of Sex Bias in Preclinical Research and How it Can Be Changed


Upsetting the status quo is never easy, especially when it comes to scientific research. Just ask AstraZeneca duo Natasha A. Karp, Associate Principal Scientist/ Biostatistician and Neil Reavey, Associate Director, Research Assurance, who explore ways of overcoming the issue of sex bias in a paper entitled, “Sex Bias in Preclinical Research and Exploration of How to Change the Status Quo.”

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12 Feb, 2019Regulatory Trends in Health Economics Outcomes Research (HEOR) & Real World Evidence (RWE)


As a relatively new means of conducting research in the life sciences, RWE, or real-world evidence, is data that comes from “real world settings” such as a clinical practice. Studies driven by real world evidence, or real-world data (RWD), can utilize data from medical records or claims databases, be conducted prospectively in observational studies or adhere to a mixed, hybrid-design approach.

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01 Feb, 2019Producing High-Quality Antibodies


Antibodies have re-shaped biomedical researches since their discovery. From research tools to therapeutics and diagnostics, antibodies are indispensable in finding cures for a host of different diseases. In recent years, antibody-based therapeutics have dramatically changed the way we treat diseases, especially in oncology. The recent introduction of platforms has further advanced how antibodies are being used.

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14 Nov, 2018iPSC Models to Improve Efficiency of Drug Discovery and Development


Stem cells have attracted a great deal of deserved attention due to their lineage-independent characteristics. In other words, they have the potential to be differentiated into a countless number of cell types. Adult stem cells, otherwise known as inducible pluripotent stem cells (iPSCs), are particularly favorable as research tools because they are derived from a patient’s somatic cells such as blood, skin or muscle.

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02 Nov, 2018RWE: Opportunity, Challenges and Sourcing Simplified  


As a relatively new means of conducting research in the life sciences, RWE, or real-world evidence, is data that comes from “real world settings” such as a clinical practice. Studies driven by real world evidence, or real-world data (RWD), can utilize data from medical records or claims databases, be conducted prospectively in observational studies or adhere to a mixed, hybrid-design approach.

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