In: Discovery & Innovation
With the fiscal cliff negotiations over for now, we turn our attention to the patent cliff. A lot of industry watchers and participants often discuss how important pharmaceutical innovation is and how patents are the key protection to garner income to cover the high costs of drug development. In the past, we’ve looked at patent-driven innovation by country and the shift from patent to generics. But why do we even need the patent system? What kind of returns are being seen on patents?Read More
We all know bacon and other fatty foods can lead to obesity, diabetes, and cardiovascular diseases but the four-legged creature from where these foods come has become an international sensation with regards to its use in scientific research. Pigs are used in efficacy and toxicity models to study cardiovascular disease, diabetes and obesity, and even has applications in dermatology and inflammation.
The pig has become a superstar in scientific research, primarily in its use as a valid animal model to study human diseases. The Swine Genome Sequencing Consortium, in their efforts to better understand pig evolution/domestication, production and health monitoring, and applications for biomedical research, has identified 112 genes in pigs that are also responsible for human metabolic disorders . With such similarities, pigs can be used for drug testing in applications of various therapeutic areas.Read More
We have seen a recent interest for Caenorhabditis elegans (C. elegans) research services and wanted to share with our users exactly how useful this little worm in pharmaceutical research is turning out to be the study of Parkinson’s Disease (PD) has led to the development of many pharmacological models from transgenic rodents to non-human primates, and now worms (the aforementioned C. elegans, to be exact).
Many researchers have taken advantage of this tiny, transparent worm to study PD as well as Alzheimer’s disease, cystic fibrosis, ALS, epilepsy, and dystonia. The worm possesses a nervous system, digestive tract, musculature and reproductive system, which are all clearly visible with the use of fluorescent proteins inserted through genetic engineering.Read More